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A patient of pulmonary tuberculosis treated with
rifampin + isoniazid + pyrazinamide developed parasthesias, weakness, dizziness, ataxia and depressed tendon reflexes. Which of the following
measures would you recommend:
A. Temporarily discontinue isoniazid and add
pyridoxine
B. Substitute isoniazid with thiacetazone
C. Substitute pyrazinamide with ethambutol
D. Substitute rifampin with streptomycin
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1 Answer

A. Temporarily discontinue isoniazid and add
pyridoxine
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