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The most important mechanism of bacterial resistance to an aminoglycoside antibiotic is:
A. Plasmid mediated acquisition of aminoglycoside conjugating enzyme
B. Mutational acquisition of aminoglycoside
hydrolysing enzyme
C. Mutation reducing affinity of ribosomal protein for the antibiotic
D. Mutational loss of porin channels
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1 Answer

A. Plasmid mediated acquisition of aminoglycoside conjugating enzyme
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