Leishmania donovani is susceptible to certain antifungal drugs because both fungi and Leishmania: A. Utilise purine salvage pathway B. Utilise similar glycolytic mechanisms C. Have similar topoisomerase II enzyme D. Have ergosterol in their cell membranes Answer : D. Have ergosterol in their cell membranes...
Vinca alkaloids exert antitumor activity by: A. Activating topoisomerase II to cause breaks in DNA strands B. Crosslinking DNA strands C. Inhibiting DNA mediated RNA synthesis D. Inhibiting polymerization of tubulin to form intracellular microtubules Answer : D. Inhibiting polymerization of tubulin to form intracellular microtubules...
Distinctive features of gatifloxacin include the following except: A. Higher affinity for the enzyme topoisomerase IV B. Activity restricted to gram negative bacteria C. Potential to prolong QTc interval D. Employed to treat community acquired pneumonia Answer : B. Activity restricted to gram negative bacteria...
Choose the correct statement about topotecan: A. It is a DNA topoisomerase I inhibitor which causes single strand DNA breaks B. It is a cell cycle specific anticancer drug C. It is a COMT-inhibitor used in advanced parkinsonism D. Both 'A' and 'B' are correc Answer : D. Both 'A' and 'B' are correct...
The enzyme which catalyzes the unwinding of DNA helix during replication is: (1) Primase (2) Topoisomerase (3) Helicase (4) DNApolymerase Answer : Helicase...
50.5k questions
47.1k answers
240 comments
7.0k users
