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Tolerance does not develop to the vasodilator action
of sodium nitroprusside while it develops to glyceryl
trinitrate because:
A. Intact sod. nitroprusside molecule acts like
nitric oxide
B. Enzymes which generate nitric oxide from
nitroprusside are different
C. Sod. nitroprusside has a long duration of
action
D. Sod. nitroprusside has additional K+ channel opening action
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1 Answer

B. Enzymes which generate nitric oxide from
nitroprusside are different
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