In order to function, CDKs must interact with members of a separate family of proteins named the cyclins. Do individual cyclins remain associated with the same CDKs throughout the entire cell cycle? Answer : No. Separate cyclins interact with specific CDKs only during defined periods of the cell cycle....
In many types of cancer, proteins that are crucial regulators of the cell cycle are often mutated and cannot function correctly. This leads to the evasion of apoptosis and to the loss of control of cell ... protein named p53. What is the normal function of p53 that is lost when it is mutated? Answer : Normally, p53 senses DNA damage and acts as a transcription factor for checkpoint control genes....
Multiple checkpoints in the eukaryotic cell cycle ensure that division occurs only after sufficient growth and faithful DNA replication, and only when favorable conditions exist. Of the many proteins involved in ... CDKs) are among the most important. How do CDKs function to control the cell cycle? Answer : CDKs phosphorylate various protein substrates that are required for cell cycle progression. Some of the important substrate proteins that CDKs phosphorylate include condensin proteins, which are essential ... which form a stabilizing network under the nuclear membrane that assembles during mitosis....
Which of the following are regularly assembled and disassembled during cell cycle. (A) Microtubules (B) Intermediate filaments (C) Both A and B (D) None of these Answer : (A) Microtubules...
The eukaryotic cell cycle consists of discrete phases. One of these is named the M or mitosis phase during which the cell divides. Following the M phase is a period known as interphase that is made up of three distinct phases. Name, in order, the three separate phases of interphase. Answer : G1, S and G2...
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