Name three classes of cell surface receptors Answer : G-protein-coupled receptors (GPCRS) - ion channel receptors - enzyme-linked receptors (example: receptor tyrosine kinases –RTKs)...
How do RTKs function? Answer : Activating signaling molecules (ligands, agonists) bind to RTKs, causing neighboring RTKs to form cross-linked dimers. Cross-linking leads to tyrosine kinase activation via cross-phosphorylation. Once ... cascade of reactions that ultimately lead to changes in the patterns of gene transcription....
What types of signaling molecules bind to and activate RTKs? Answer : Growth factors, hormones, some extracellular matrix proteins, some cell surface proteins (i.e. ephrin)...
List several general cellular processes regulated by receptor tyrosine kinases (RTKs). Answer : Cell growth, cell differentiation and cell survival (i.e. nutrient and stress signaling)....
Tissues are constructed from many distinct cell types that perform different functions in response to signals from each other and the extracellular matrix. During tissue development and tissue regeneration, ... that stem cells undergo when they are required to generate a particular type of cell? Answer : Asymmetric cell division. After asymmetric division, each of the two resulting daughter cells has a unique life course. For example, one daughter cell may differentiate into a specific cell type ( ... cell), whereas the other daughter cell may remain a stem cell with unlimited proliferative ability....
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