11. Which route of drug administration is most likely to lead to the first-pass effect? a) Sublingual b) Oral c) Intravenous d) Intramuscular Answer : b) Oral...
12. What is characteristic of the oral route? a) Fast onset of effect b) Absorption depends on GI tract secretion and motor function c) A drug reaches the blood passing the liver d) The sterilization of medicinal forms is obligatory Answer : b) Absorption depends on GI tract secretion and motor function...
08. What does the term bioavailability mean? a) Plasma protein binding degree of substance b) Permeability through the brain-blood barrier c) Fraction of an uncharged drug reaching the systemic ... following any route administration d) Amount of a substance in urine relative to the initial doze Answer : c) Fraction of an uncharged drug reaching the systemic circulation following any route administration...
13. Tick the feature of the sublingual route: a) Pretty fast absorption b) A drug is exposed to gastric secretion c) A drug is exposed more prominent liver metabolism d) A drug can be administrated in a variety of doses
Drug administered through the following route is most likely to be subjected to first-pass metabolism: A. Oral B. Sublingual C. Subcutaneous D. Rectal Answer : A. Oral...
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